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Acute liver failure is rare in children. Associated hepatic encephalopathy has a poor prognosis, but aggressive management with high dose continuous renal replacement therapy (CRRT) and plasma exchange (PE) can be life -saving.
Most Recent References
North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position Paper on the Diagnosis and Management of Pediatric Acute Liver Failure. Squires JE, Alonso EM, Ibrahim SH, Kasper V, Kehar M, Martinez M, Squires RH. J Pediatr Gastroenterol Nutr. 2022 Jan 1;74(1):138-158.
Advances in medical management of acute liver failure in children: promoting native liver survival. Deep A, Alexander EC, Bulut Y, Fitzpatrick E, Grazioli S, Heaton N, Dhawan A. Lancet Child Adolesc Health. 2022 Oct;6(10):725-737.
Analysis of the clinical characteristics of the liver injury induced by levetiracetam. Sun W, He Y, Li Z, Wang C. J Pharm Pharmacol. 2022 Mar 3;74(3):409-414.
