Brief Resolved Unexplained Events (BRUE)

Last Updated: September 11th, 2023
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Overview

The document discusses our approach to brief resolved unexplained events (BRUE) in infants younger than one year of age. The term BRUE has replaced the older term of acute life-threatening events (ALTE).

Most Recent References

  • Diagnostic Testing for Evaluation of Brief Resolved Unexplained Events. Mittal MK, Tieder JS, Westphal K, Sullivan E, Hall M, Bochner R, Cohen A, Colgan JY, Delaney AC, DeLaroche AM, Graf T, Harper B, Kaplan RL, Beubauer HC, Neuman MI, Shastri N, Wilkins V, Stephans A. Acad Emerg Med. Published online February 10, 2023:acem.14666. doi:10.1111/acem.14666.

  • Risk Prediction After a Brief Resolved Unexplained Event. Nama N, Hall M, Neuman M, Sullivan E, Bochner R, De Laroche A, Hadvani T, Jain S, Katsogridakis Y, Kim E, Mittal M, Payson A, Prusakowski M, Shastri N, Stephans A, Wesphal K, Wilkins V, Tieder J; Brief Resolved Unexplained Event Research and Quality Improvement Network. Hosp Pediatr. 2022;12(9):772-785. doi:10.1542/hpeds.2022-006637.

  • Explanatory Diagnoses Following Hospitalization for a Brief Resolved Unexplained Event. Bochner R, Tieder JS, Sullivan E, Hall M, Stephans A, Mittal MK, Signh N, Delaney A, Harper B, Shastri N, Hochreiter D, Neuman MI; Brief Resolved Unexplained Event Research and Quality Improvement Network. Pediatrics. 2021;148(5):e2021052673. doi:10.1542/peds.2021-052673.