Overview
This document supplements the DKA (Diabetic Ketoacidosis) Summary document and addresses specifically the recognition and management of cerebral edema in DKA.
Most Recent References
Increasing use of hypertonic saline over mannitol in the treatment of symptomatic cerebral edema in pediatric diabetic ketoacidosis: an 11-year retrospective analysis of mortality*. Decourcey DD, Steil GM, Wypij D, Agus MS. Pediatr Crit Care Med. 2013 Sep;14(7):694-700.
Pediatric diabetic ketoacidosis, fluid therapy, and cerebral injury: the design of a factorial randomized controlled trial. Glaser NS, Ghetti S, Casper TC, Dean JM, Kuppermann N; Pediatric Emergency Care Applied Research Network (PECARN) DKA FLUID Study Group. Pediatr Diabetes. 2013 Sep;14(6):435-46.
Increasing use of hypertonic saline over mannitol in the treatment of symptomatic cerebral edema in pediatric diabetic ketoacidosis: an 11-year retrospective analysis of mortality*. Decourcey DD, Steil GM, Wypij D, Agus MS. Pediatr Crit Care Med. 2013 Sep;14(7):694-700.